Tretinoin does the heavy lifting
It speeds up skin cell turnover, which can soften fine lines and even out texture over time.
NightlyRxImportant safety information
Estriol + tretinoin cream
This cream combines tretinoin, a retinoid that speeds up skin renewal, with estriol, used topically to support skin firmness. It's applied at night and prescribed after an online visit.
$118/monthBilled monthly
$103.72 your first month with code WELCOME20New patients save $14.28
Meet Estriol + tretinoin cream
This cream combines tretinoin, a retinoid that speeds up skin renewal, with estriol, used topically to support skin firmness. It's applied at night and prescribed after an online visit.
How it works
A nightly cream for fine lines, texture and tone. Prescription-strength retinoid. 30 g tube, one- or three-month supply. Mixed by a licensed compounding pharmacy.
How to use it
Apply a pea-sized amount to clean, dry skin at night. Start every other night, then build up as your skin adjusts. Use broad-spectrum sunscreen every morning.
Form and dosing
Nightly cream. At night. Prepared by a licensed compounding pharmacy.
Compounded medicines are prepared by a licensed pharmacy for an individual prescription. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality. Prescription required.
MedBrain makes it simple
Get started todayFree online visit
Answer a few questions about your goals. MedBrain suggests where to start.
A licensed provider reviews it
They read your full medical intake and decide whether treatment is right for you.
Discreet delivery
If prescribed, a licensed pharmacy ships your treatment in plain packaging.
Ongoing support
Message your care team with questions and adjust your plan as you go.
How skin treatment works
Get startedStart slowly
Dryness and peeling are common in the first weeks. Using it every other night at first helps your skin adjust.
Sunscreen is part of the plan
Retinoids make skin more sensitive to sunlight. Daily SPF protects your skin and your results.
Why people choose Estriol + tretinoin cream
- Prescription-strength retinoid
- 30 g tube, one- or three-month supply
- Mixed by a licensed compounding pharmacy
More skin treatments
Custom skin formulation
Starting at $56 per month
Choose a GHK-Cu, estriol or tretinoin formulation with your provider.
Important safety informationEstriol + tretinoin cream questions
Find my treatmentWhy estriol?
Topical estriol is used to support skin thickness and firmness, particularly for skin affected by hormonal changes.
Can I use it around my eyes?
Keep it away from the eyes, nostrils and lips. Ask your provider about using it on delicate areas.
Important safety information
Estriol + tretinoin cream is a prescription treatment. A licensed provider reviews your medical history before deciding whether it’s right for you.
- Do not use during pregnancy, while breastfeeding or while trying to conceive.
- Redness, dryness and peeling are common in the first weeks.
- Avoid using other strong exfoliants at the same time unless your provider says otherwise.
Compounded medicines are prepared by a licensed pharmacy for an individual prescription. They are not FDA-approved, and the FDA does not verify their safety, effectiveness or quality. Tell your provider about all medicines you take and any health conditions you have. Estriol + tretinoin cream may not be right for everyone.
Product images are for illustration only; actual product appearance and labeling will differ. MedBrain does not manufacture or compound medications.
From $56/moGet started